Journal of Nephrology and Renal Transplantation,  Vol 10, No 1

ALLOGRAFT SURVIVAL RATE AND ANALYSIS OF PREDICTOR FACTORS IN KIDNEY TRANSPLANT RECIPIENTS FROM LIVING DONORS

Ali Monfared

Abstract


Introduction: Renal transplantation is the modality of choice for renal replacement therapy in the majority of end stage renal disease patients. The aim of this study is to determine graft survival rate and possible related factors in 273 living donor renal transplant recipients in the same center from 1999 to 2010.

 

Material and Methods: Organ survival and demographic characteristics and variables that may affect graft survival rate were evaluated in all renal allograft recipients in Razi Hospital of Rasht in North of Iran. Chi-square, Independent T-Test and Mann-Whitney were used for analysis of urivariates. Survival rate was estimated by “Kaplan-Meier method”, and Tarone-Ware test were applied for comparing survival rates. Multivariate analysis was also done by COX regression model.

Results: In this study, 1, 5 and 10 year graft survival rates were 92.6±1.6, 88±2.1 and 77.5±3.9%, respectively. The mean age of donors and recipients was 30.43±5.99 and 39.09±13.02, respectively. 95.6% of donors and 60.7% of recipients were male who have been followed for 10 years after renal transplantation (RT). Delayed graft function was significantly correlated with graft survival rate (P


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