Patient and Graft Outcome among Filipino post Kidney Transplant Pregnancies
Background:Kidney transplantation (KT) has shown to improve fertility rates among women post-transplant. However, despite the favorable outcome, the impact of pregnancy on the graft as well as the effect on the fetus should be considered. In addition, these patients are exposed to anti-rejection medications which could affect the fetus.
Objective: To describe the graft and pregnancy outcomes among KT recipients
Methodology: Descriptive study among 32 post-KT recipients who had pregnancy from January 1, 2001 to December 31, 2016 and were followed-up to 3-month post-partum. Each pregnancy was considered as an event.
Results:There were 32 post-KT patients with 38 pregnancies. Mean age during conception was 34 years, with mean interval from KT to pregnancy of 4.8 years. Around 84% with cyclosporine-based immunosuppression. The mean pre-natal serum creatinine was 1.15 mg/dl, 5.3% had ≥1.5 mg/dl pre-natal creatinine and 10.5% rejection rate. There were 94% live births, 18.42% pre-eclampsia, 3% eclampsia, 3% abortion, and 3% stillbirth. There were 68% unplanned pregnancies and more complications were observed among these patients.
Conclusion:The maternal and fetal outcomes and complications in this study were comparable with other studies. However, most of these complications were observed among the unplanned pregnancies. Hence counselling prior to pregnancy should be emphasized.
Keywords:Gestation, perinatal period, gravid, renal transplant, Philippines
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