Journal of Nephrology and Renal Transplantation,  Vol 10, No 2

Small Cell Lung Cancer Presenting as Hyponatremia: A Case Report

Alborz Sherafati


Background - Euvolemic hyponatremia caused by hypothyroidism, drugs, stress, glucocorticoid deficiency and syndrome of inappropriate antidiuretic hormone secretion(SIADH)(1,2,3,4).

SIADH is the most frequent cause of euvolemic hyponatremia (1,4).

A 45 years old man presented with persistent nausea, vomiting and epigastric pain in emergency department. Primary assessment defined normotension, elevated amylase and lipase more than 3-fold the upper limit of normal, and severe hyponatremia.

He admitted in general ward with diagnosis of pancreatitis.

We approach to euvolemic hyponatremia and detected hypouricemia, normal TSH and normal serum cortisol (8AM).

Because of history of smoking and suspicion of SIADH we requested CXR.

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